3-CHLORO-4-METHOXYBENZENEBORONIC ACID

3-CHLORO-4-METHOXYBENZENEBORONIC ACID - Names and Identifiers

Name	3-CHLORO-4-METHOXYPHENYLBORONIC ACID
Synonyms	AKOS BRN-0653 4-Borono-2-chloroanisole 3-CHLORO-4-METHOXYPHENYLBORONIC ACID (3-chloro-4-Methoxyphenyl)boranediol 3-CHLORO-4-METHOXYBENZENEBORONIC ACID (3-chloro-4-ethoxyphenyl)boronic acid B-(3-Chloro-4-methoxyphenyl)boronic acid Boronic acid, B-(3-chloro-4-methoxyphenyl)- 3-Chloro-4-methoxyphenylboronic Acid (contains varying amounts of Anhydride)
CAS	175883-60-0
InChI	InChI=1/C8H10BClO3/c1-2-13-8-4-3-6(9(11)12)5-7(8)10/h3-5,11-12H,2H2,1H3

3-CHLORO-4-METHOXYBENZENEBORONIC ACID - Physico-chemical Properties

Molecular Formula	C7H8BClO3
Molar Mass	186.4
Density	1.32
Melting Point	238-242 °C (lit.)
Boling Point	344.8±52.0 °C(Predicted)
Flash Point	168°C
Solubility	soluble in Methanol
Vapor Presure	1.26E-05mmHg at 25°C
Appearance	Solid
Color	White to Almost white
pKa	7.93±0.10(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.537
MDL	MFCD04039888
Physical and Chemical Properties	WGK Germany:3

3-CHLORO-4-METHOXYBENZENEBORONIC ACID - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection S60 - This material and its container must be disposed of as hazardous waste. S37 - Wear suitable gloves.
WGK Germany	3
HS Code	29319090
Hazard Class	IRRITANT, KEEP COLD

3-CHLORO-4-METHOXYBENZENEBORONIC ACID - Introduction

ACID is an organic compound with the formula C7H8BLO2. The following is a detailed description of its nature, use, preparation and safety information:

Nature:
-Appearance: ACID is a white solid.
-Solubility: Soluble in organic solvents such as esters and ethers, insoluble in water.
-Melting point: About 116-118 degrees Celsius.
-Stability: Stable to light, heat and air.

Use:
-acrylic is a reagent commonly used in organic synthesis. It can be used as a starting material for the synthesis of aromatic compounds, such as flavors, pharmaceutical intermediates and coupling reagents in organic synthesis.
-In organic synthesis, it can be used for the coupling reaction between benzene ring and nitrile compounds.
-In addition, it can also be used in the preparation of electronic devices such as organic light-emitting diodes (OLED).

Method:
-The synthesis method of ACID can be obtained by the reaction of Phenylboronic ACID and 3-chloro-4-methoxyphenyl fluoroborate.
-The reaction conditions are usually carried out under an inert atmosphere, and the yield is improved by temperature control.

Safety Information:
-acrylic is irritating and should avoid contact with skin and eyes. Wear appropriate personal protective equipment such as goggles, protective gloves, etc. during use.
-Avoid contact with oxidants and strong acids such as strong sulfuric acid to avoid dangerous reactions.
-When storing, keep it in a dry, cool place, away from fire and combustibles.

Last Update：2024-04-09 20:52:54